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Discussion

Which of the following takes place due to phosphorylation of isocitrate dehydrogenase?

  • A.Inhibits the binding of citrate at active site
  • B.Degrades the enzyme
  • C.Enhances the substrate-binding affinity
  • D.No reaction

Answer: A

The electrostatic repulsion by the phosphoryl group inhibits the binding of citrate at active site.

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