Discussion

Which of the following choices describes a way to graphically determine the type of inhibition being displayed by an inhibitor?

I. Plot initial reaction rate versus the concentration of substrate for the uninhibited enzyme, and then compare to the inhibited enzyme

II. Plot the inverse of the initial reaction rate versus the inverse of the substrate concentration for the uninhibited enzyme, and then compare to the inhibited enzyme

III. Plot the concentration of the inhibitor versus the concentration of substrate