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DNA Replication

11.

What bands will be observed in a cesium chloride gradient after two rounds of replication?

Answer: B

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12.

The DNA polymerase in bacteria, responsible for DNA synthesis is

Answer: C

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13.

There is a single origin for DNA replication in bacteria. How many origins of replication are found in the much larger genomes of eukaryotes such as mammals?

Answer: C

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14.

The replication of a linear DNA molecule in a eukaryotic chromosome creates a problem which is reported to be sorted out by

Answer: A

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15.

Which of the following reactions is required for proofreading during DNA replication by DNA polymerase III?

Answer: B

The 3’ → 5’ exonuclease activity removes the mispaired nucleotide and the polymerase begins again. This activity is known as proofreading.

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16.

Which histone(s) are associated with the linker DNA of a nucleosome?

Answer: A

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Answer: B

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Answer: C

DNA ligase catalyzes the formation of a phosphodiester bond between 3’-OH of one Okazaki fragment and 5’-phosphate of the next.

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19.

What is a mode of replication in E.coli?

Answer: D

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20.

Which of the following helps in opening of DNA double helix in front of replication fork?

Answer: C

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